Elisabeth's November 2013 pick
The Rosie Project, by Graeme Simsion
A hilarious romp narrated by Simon, a brilliant geneticist who, despite his lack of understanding social cues, embarks on a scientific campaign to find a wife, reasoning that companionship would be practical and convenient. His method of evaluating candidates, a lengthy questionnaire to ensure compatibility before investing time and effort, turns away several fantastic candidates, and his inability to pick up on social cues turns away several beautiful and brilliant and definitely interested women.
It is Rosie, a wholly inappropriate candidate (according to his questionnaire) who begins to mold Simon in to regular life as they work towards solving the mystery of Rosie's father (he's a geneticist, remember?).
The author is very careful not to label Simon as autistic, although autism and Asperger's Syndrome are mentioned, because the label would flatten this rich character into a two dimensional figure. Simon does have many characteristics that only he does not seem to notice, and has a very particular way of viewing the world that makes for a fascinating narrative, and it makes him a sympathetic and likeable character even as you scream at him to notice what is going on around him.